Cognition Changes in Patients with Atrial Fibrillation

 


   Note: An Official Proposal has not been Submitted to NACC.


   Lead Investigator:    Kathryn Wood
   Institution      :    Emory University School of Nursing
   E-Mail           :    kathryn.wood@emory.edu
   Proposal ID      :    1676



   Proposal Description:
   This data analysis would serve as pilot data for future project to test the hypothesis that patients with atrial fibrillation (AF) have more cognitive decline than patients without AF.  this would also provide an opportunity to explore cognition and genetic/biomarker changes in patients with AF.      Aims: (1) to determine if patients with AF and and normal cognition at baseline have more rapid cognitive decline (to MCI or AD) over time than subjects with normal cognition who do not have AF.     (2) to determine if patients with AF and MCI at baseline have more rapid cognitive decline over time than subjects with MCI who do not have AF.    (3) to determine if Aim 2 or 2 differ by gender or race     (4) to identify any specific genetic/biomarker data associated with cognitive decline in AF patients compared to those patients without AF.